RNF181 Antibody, Biotin conjugated
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中文名稱：RNF181兔多克隆抗體, Biotin偶聯(lián)
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貨號：CSB-PA019860LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) RNF181 Polyclonal antibody
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Uniprot No.：
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基因名：RNF181
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別名：RNF181 antibody; HSPC238 antibody; E3 ubiquitin-protein ligase RNF181 antibody; EC 2.3.2.27 antibody; RING finger protein 181 antibody; RING-type E3 ubiquitin transferase RNF181 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human E3 ubiquitin-protein ligase RNF181 protein (2-153AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
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靶點詳情
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功能：E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
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基因功能參考文獻：
- The identification and validation of proteins interacting with HSP238 may lead to the discovery of novel mechanisms through which HSPC238 suppresses tumorigenesis in human hepatocellular carcinoma PMID: 26398855
- RNF181 limits the proliferation of human diffuse large B cell lymphoma cells that depend upon aberrant CARD11 signaling to NF-kappaB for growth and survival in culture. PMID: 26711259
- RN181 suppresses the tumorigenesis of hepatocellular carcinoma through the inhibition of ERK/MAPK signaling in the liver. PMID: 21391225
- Data show LOC51255 (RNF181) protein located in the cytoplasm of HePG2 cell line. PMID: 19426595
- The presence of RN181 in human platelets was established; RN181 has ubiquitin E3 ligase activity. PMID: 18331836
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蛋白家族：RNF181 family
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組織特異性：Widely expressed, with highest levels in liver and heart and lowest levels in brain and skeletal muscle. Expressed in platelets (at protein level).
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數(shù)據(jù)庫鏈接：
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