RND2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RND2 Polyclonal antibody
Uniprot No.：

P52198
基因名：

RND2
別名：

ARHN antibody; CTD-3199J23.4 antibody; GTP-binding protein Rho7 antibody; ras homolog gene family, member N antibody; Rho 7 antibody; Rho family GTPase 2 antibody; Rho N antibody; Rho related GTP-binding protein RhoN antibody; Rho-related GTP-binding protein Rho7 antibody; Rho-related GTP-binding protein RhoN antibody; Rho7 antibody; RhoN antibody; Rnd 2 antibody; Rnd2 antibody; RND2_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Rho-related GTP-binding protein RhoN protein (104-163AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily.
基因功能參考文獻：
1. Rho7 expression was increased in the neurons of patients with IE compared with control samples, which indicated that Rho7 may be associated with the progression of IE or act as a potential target for IE treatment. PMID: 29039551
2. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers PMID: 11940653
3. The RND2 mRNA levels increased significantly after gestation in myometria. PMID: 16311049
4. Rnd2 regulates neurite outgrowth by functioning as the RhoA activator through Pragmin, in contrast to Rnd1 and Rnd3 inhibiting RhoA signaling PMID: 16481321
亞細胞定位：

Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Rho family
組織特異性：

Highly expressed in testis.
數據庫鏈接：

HGNC: 18315

OMIM: 601555

KEGG: hsa:8153

STRING: 9606.ENSP00000466680

UniGene: Hs.603111

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