RHOQ Antibody
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中文名稱：RHOQ兔多克隆抗體
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貨號：CSB-PA019693GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：ARHQ antibody; Ras homolog gene family member Q antibody; RAS like family 7 member A antibody; Ras like protein family member 7A antibody; Ras like protein TC10 antibody; Ras related GTP binding protein TC10 antibody; Ras-like protein family member 7A antibody; Ras-like protein TC10 antibody; RASL7A antibody; Rho related GTP binding protein RhoQ antibody; Rho-related GTP-binding protein RhoQ antibody; Rhoq antibody; RHOQ_HUMAN antibody; TC10A antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human RHOQ
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
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基因功能參考文獻：
- Exocytosis of Rab11- and L1-positive vesicles may play a central role in TC10-mediated neurite outgrowth PMID: 24223996
- Novel tumor-associated increase of RNA editing in ras homologue family member Q (RHOQ) transcripts, is reported. PMID: 24663214
- The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin PMID: 12687004
- Overexpression of the Rho family member TC10alpha, disrupts adipocyte cortical actin structure and inhibits insulin-stimulated GLUT4 translocation PMID: 12972548
- The GTP-bound form of TC10 directs the trafficking of CFTR from the juxtanuclear region to the secretory pathway toward the plasma membrane PMID: 15546864
- The crystal structure of TC10 proved that the basic region of WASp and two unique glutamates in Cdc42 generate favorable electrostatic steering forces that control the accelerated WASp-Cdc42 association reaction. PMID: 16246732
- We propose that an EGF-stimulated GAP accelerates GTP hydrolysis of TC10, thereby promoting vesicle fusion. PMID: 16950130
- These findings reveal a novel signaling pathway in human skeletal muscle that involves obscurin and the Rho GTPase TC10 and implicate this pathway in new sarcomere formation. PMID: 19258391
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亞細胞定位：Cytoplasm. Cell membrane; Lipid-anchor.
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蛋白家族：Small GTPase superfamily, Rho family
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數據庫鏈接：
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