RFX5 Antibody
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中文名稱：RFX5兔多克隆抗體
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貨號：CSB-PA019614GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：DNA binding protein RFX 5 antibody; DNA binding protein RFX5 antibody; DNA-binding protein RFX5 antibody; Influences HLA class II expression antibody; Regulatory factor X 5 antibody; Regulatory factor X subunit 5 antibody; Regulatory factor X; 5 (influences HLA class II expression) antibody; RFX 5 antibody; RFX5 antibody; Rfx5 protein antibody; RFX5_HUMAN antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Human RFX5
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.
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基因功能參考文獻：
- RFX5 acts as a direct positive transcriptional regulator of TPP1 in hepatocellular carcinoma. PMID: 27840983
- Data show arginine methyltransferase PRMT6 methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression. PMID: 23911394
- these data have identified as novel pathway whereby SIRT1 maintains COL1A2 synthesis in SMCs by modulating RFX5 activity. PMID: 23079621
- RFXAP(C) consists of two alpha-helices that form a V-shaped structure that packs within the RFX5(N)(2) staple. PMID: 20732328
- interaction at COL1A2 start site and transcription repression PMID: 11986307
- The mutation for the fifth Bbare lymphocyte syndrome complementation group was found in RFX5 and was mapped to one of the arginines in a DNA-binding surface of this protein. Its wild-type counterpart restored function. PMID: 12368908
- RFX5 binds to the collagen transcription start site and represses collagen gene expression PMID: 12968017
- The identification of nuclear import and export sites on RFX molecules provides potential targets to modulate MHC class II expression. PMID: 15210800
- RFXAP and RFXB have roles in relieving autoinhibition of RFX5 PMID: 18723135
- TSA treatment enhances the association of CIITA with the transcription factor RFX5, which ameliorates the down-regulation of CIITA recruitment to target promoters by HDAC2. PMID: 19041327
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相關(guān)疾?。?/div>Bare lymphocyte syndrome 2 (BLS2)亞細胞定位：Nucleus.蛋白家族：RFX family組織特異性：Ubiquitous.數(shù)據(jù)庫鏈接：
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