RFPL3 Antibody, Biotin conjugated

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) RFPL3 Polyclonal antibody
Uniprot No.：

O75679
基因名：

RFPL3
別名：

RFPL3 antibody; Ret finger protein-like 3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Ret finger protein-like 3 protein (8-288AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Biotin
克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

(Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex.
基因功能參考文獻(xiàn)：
1. EGF significantly upregulated RFPL3 and hTERT protein levels in the nonsmall cell lung cancer cells. RFPL3 and hTERT proteins upregulation by EGF were attenuated by pretreatment with AG1478 and erlotinib. EGF promoted proliferation and inhibited apoptosis; PD98059 decreased RFPL3 and hTERT protein expression; and RFPL3 overexpression increased the expression of hTERT and related MEKpathway proteins PMID: 29749533
2. RFPL3 and CBP have roles in upregulating hTERT activity and promoting lung cancer growth PMID: 26318425
3. These results demonstrate that RFPL3 is an important cellular factor which promotes lung cancer growth by activating hTERT expression PMID: 25481043
4. RFPL3 is a potential stimulator of human immunodeficiency virus, type 1 (HIV-1) preintegration complex integration. PMID: 25107902
5. the human RFPL1,2,3 genes have a role in neocortex development PMID: 18656177
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亞細(xì)胞定位：

Cytoplasm. Nucleus.
組織特異性：

Expressed during neurogenesis in differentiating human embryonic stem cells and in the developing human neocortex.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 9980

OMIM: 605970

KEGG: hsa:10738

STRING: 9606.ENSP00000249007

UniGene: Hs.558455

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