RFC4 Antibody

說明書

產品詳情

Uniprot No.：

P35249
基因名：

RFC4
別名：

A1 37 antibody; A1 37 kDa subunit antibody; Activator 1 37 antibody; Activator 1 37 kDa subunit antibody; Activator 1 subunit 4 antibody; Replication factor C 37 antibody; Replication factor C 37 kDa subunit antibody; Replication factor C subunit 4 antibody; Replication factor C4 antibody; RF-C 37 kDa subunit antibody; RFC 37 antibody; RFC37 antibody; RFC4 replication factor C (activator 1)4 37kDa antibody; RfC4 antibody; RFC4_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human RFC4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.
基因功能參考文獻：
1. Expression level of RFC4 was up regulated in cervical squamous cell carcinoma. PMID: 28341182
2. RFC4 is frequently overexpressed in CRC, and is associated with tumor progression and worse survival outcome. This might be attributed to the regulation of CRC cell proliferation and cell cycle arrest by RFC4 PMID: 25407051
3. The knockdown of endogenous replication factor C4 decreases the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. PMID: 18492021
亞細胞定位：

Nucleus.
蛋白家族：

Activator 1 small subunits family
數據庫鏈接：

HGNC: 9972

OMIM: 102577

KEGG: hsa:5984

STRING: 9606.ENSP00000296273

UniGene: Hs.732098

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