RER1 Antibody, Biotin conjugated
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中文名稱：RER1兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA019567LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) RER1 Polyclonal antibody
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Uniprot No.：
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基因名：RER1
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別名：RER1; Protein RER1
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Protein RER1 protein (85-139AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
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基因功能參考文獻：
- RER1 is a novel and potential important mediator of elevated alphaSyn levels PMID: 28877262
- Rer1p regulates the ER retention of immature or misfolded rhodopsin and modulates its intracellular trafficking through the early secretory pathway. PMID: 25096327
- Charcot-Marie-Tooth disease-related PMP22 is trapped in the endoplasmic reticulum by calnexin-dependent retention and Rer1-mediated early Golgi retrieval systems and partly degraded by the Hrd1-mediated endoplasmic reticulum-associated degradation system. PMID: 25385046
- Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch signaling as well as reducing Foxj1a expression. PMID: 23479743
- Synoviolin up-regulates amyloid beta production by targeting a negative regulator of gamma-secretase, Rer1, for degradation. PMID: 23129766
- RER1 modulates amyloid-beta production by altering trafficking of gamma-secretase and amyloid precursor protein. PMID: 23043097
- Downregulation of Rer1 leads to increased surface localization of Pen2, whereas overexpression of Rer1 stabilizes unassembled Pen2. Rer1 is the first identified interaction partner of mammalian transmembrane-based retention/retrieval signals. PMID: 17668005
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亞細胞定位：Golgi apparatus membrane; Multi-pass membrane protein.
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蛋白家族：RER1 family
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數據庫鏈接：
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