RCBTB1 Antibody
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中文名稱：RCBTB1兔多克隆抗體
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貨號：CSB-PA030187
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：RCBTB1
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別名：Chronic lymphocytic leukemia deletion region gene 7 protein antibody; CLL deletion region gene 7 protein antibody; CLLL7 antibody; CLLL7 protein antibody; E4.5 antibody; GDP/GTP exchange factor (GEF) like protein antibody; GLP antibody; Guanine nucleotide exchange factor antibody; Hypothetical protein FLJ39335 antibody; RCBT1_HUMAN antibody; Rcbtb1 antibody; RCC1 and BTB domain-containing protein 1 antibody; Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 antibody; Regulator of chromosome condensation and BTB domain-containing protein 1 antibody; RP11-185C18.1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthesized peptide derived from the Internal region of Human CLLD7.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：May be involved in cell cycle regulation by chromatin remodeling.
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基因功能參考文獻：
- Data indicate RNA Binding Protein with Multiple Splicing (RBPMS), Regulator of Chromosome Condensation and POZ Domain Containing Protein 1 (RCBTB1), and Zinc Finger protein 608 (ZNF608) as miR-21-3p target genes. PMID: 27166999
- study puts forward mutations in RCBTB1 as a cause of autosomal-recessive non-syndromic and syndromic inherited retinal dystrophies; data support a role for impaired ubiquitination in the pathogenetic mechanism of RCBTB1 mutations PMID: 27486781
- Results identified RCBTB1 as a gene associated with vitreoretinopathy and found that it plays a role in retinal angiogenesis through Norrin-induced beta-catenin signaling. PMID: 26908610
- Study identifies RCBTB1 as a modifier of the smoking effect on carotid intima-media thickness. PMID: 24202307
- Data show that the biological actions of Clld7 are consistent with those of a tumor suppressor. PMID: 20926398
- E4.5 gene, which maps at chromosome band 13q14.3, encodes for a 4 kb mRNA expressed in various tissues and has an open reading frame of 531 amino acids. It has a potential role in the pathogenesis of chronic lymphocytic leukemia [E4.5] PMID: 14565662
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相關疾?。?/div>Retinal dystrophy with or without extraocular anomalies (RDEOA)亞細胞定位：Nucleus.組織特異性：Ubiquitously expressed. In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level).數據庫鏈接：
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