RAP2C Antibody
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中文名稱：RAP2C兔多克隆抗體
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貨號：CSB-PA003939
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規(guī)格：￥1090
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圖片：
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Western Blot analysis of MCF7 cells using Rap 2C Polyclonal Antibody
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：RAP2C
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別名：2010200P20Rik antibody; AI194294 antibody; AL022976 antibody; BOS_25229 antibody; DKFZp313B211 antibody; MGC143331 antibody; OTTHUMP00000024037 antibody; OTTMUSP00000019067 antibody; RAP2C antibody; RAP2C; member of RAS oncogene family antibody; RAP2C_HUMAN antibody; Ras related protein Rap 2c antibody; Ras-related protein Rap-2c antibody; RP23-15D12.2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Synthesized peptide derived from the Internal region of Human Rap 2C.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.
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基因功能參考文獻：
- Study found that SCII upregulated the expression of miR-204 and downregulated the expression of RAP2C; that hypoxia increased the expression of miR-204 and decreased the expression of RAP2C, and overexpression of RAP2C attenuates the effect of hypoxia on apoptosis rate; and miR-204 could directly bind to RAP2C, and could regulate the expression of RAP2C. PMID: 28714326
- JAM-A regulates epithelial permeability via association with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and control contraction of the apical cytoskeleton. PMID: 23885123
- This work demonstrates that Rap2C is a new member of the Rap2 subfamily of proteins, able to bind guanine nucleotides with peculiar properties, and differently expressed by various hematopoietic subsets PMID: 16213650
- RAP2C is a novel member of the Ras family, belonging to the Rap branch of small GTPase proteins and may be involved in SRE-mediated gene transcription. PMID: 17447155
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亞細胞定位：Cytoplasm. Recycling endosome membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Small GTPase superfamily, Ras family
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組織特異性：Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
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數(shù)據(jù)庫鏈接：
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