RAB6B Antibody
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中文名稱：RAB6B兔多克隆抗體
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貨號(hào)：CSB-PA019217GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：RAB6B
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別名：9630015C03 antibody; AI844641 antibody; C330006L04Rik antibody; D9Bwg0185e antibody; OTTHUMP00000216372 antibody; RAB6B antibody; RAB6B member RAS oncogene family antibody; RAB6B_HUMAN antibody; Ras related protein Rab 6B antibody; Ras-related protein Rab-6B antibody; Small GTP binding protein antibody; Small GTPase RAB6B antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human RAB6B
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情
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功能：Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
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基因功能參考文獻(xiàn)：
- Conformational changes in human neuronal Rab6B between its inactive GDP and active GTP-like state are observed mainly in the switch I and switch II regions, confirming their role as a molecular switch. PMID: 16790928
- The brain-specific Rab6B via Bicaudal-D1 is linked to the dynein/dynactin complex, suggesting a regulatory role for Rab6B in the retrograde transport of cargo in neuronal cells. PMID: 17707369
- DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi. PMID: 18044744
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亞細(xì)胞定位：Golgi apparatus membrane; Lipid-anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle.
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蛋白家族：Small GTPase superfamily, Rab family
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組織特異性：Predominantly expressed in brain.
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數(shù)據(jù)庫鏈接：
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