RAB3D Antibody
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中文名稱：RAB3D兔多克隆抗體
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貨號：CSB-PA955238
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA955238(Rab3D Antibody) at dilution 1/27, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA955238(Rab3D Antibody) at dilution 1/27, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：D2-2 antibody; Glioblastoma overexpressed antibody; GOV antibody; RAB 16 antibody; RAB16 antibody; Rab3d antibody; Rab3D upregulated with myeloid differentiation antibody; RAB3D; member RAS oncogene family antibody; RAB3D_HUMAN antibody; RAD3D antibody; Ras-related protein Rab-3D antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthetic peptide of Human Rab3D
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:10000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Protein transport. Probably involved in regulated exocytosis.
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基因功能參考文獻：
- targeting the Rab3D may be a potential therapeutic target for treatment of esophageal squamous cell carcinoma. PMID: 28472755
- increased Rab3D expression is associated with invasiveness of CRC cells PMID: 27046094
- High expression of small GTPase Rab3D promotes cancer progression and metastasis. PMID: 25823663
- The presence of Rab3D(N135I) decreases the restriction of maturing secretory granules (SGs) to the F-actin-rich cell cortex, blocks the removal of the endoprotease furin from SGs and impedes the processing of the luminal SG protein secretogranin II. PMID: 23526941
- Our findings indicate that Rab3D regulates the exocytosis of many components critical for the maintenance of oral physiology. PMID: 21702009
- MIST1 binds to highly conserved CATATG E-boxes to directly activate transcription of 6 genes, including those encoding the small GTPases RAB26 and RAB3D. PMID: 20038531
- mutant Rab3D proteins interfere with the formation of bona fide Weibel-Palade bodies and consequently the acute, histamine-induced release of von-Willebrand factor PMID: 15257287
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亞細胞定位：Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Small GTPase superfamily, Rab family
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組織特異性：Highly expressed in granulocytes of peripheral blood. Constitutively expressed at low levels in all hematopoietic cell lines investigated.
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數據庫鏈接：
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