RAB37 Antibody
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中文名稱：RAB37兔多克隆抗體
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貨號：CSB-PA009267
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規格：￥1090
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其他：
產品詳情
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Uniprot No.：
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基因名：RAB37
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別名：B230331O03Rik antibody; B230354I04Rik antibody; FLJ30284 antibody; FLJ32507 antibody; GTPase Rab37 antibody; MGC157622 antibody; OTTMUSP00000003775 antibody; RAB 37 antibody; Rab37 antibody; Rab37 like antibody; RAB37 member RAS oncogene family antibody; RAB37_HUMAN antibody; Ras related protein Rab 37 antibody; Ras related protein Rab37 antibody; Ras-related protein Rab-37 antibody; RP23-342L24.2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the C-terminal region of Human Rab 37.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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基因功能參考文獻：
- Our findings suggest that Rab37-mediated TSP1 secretion in cancer cells suppresses metastasis and angiogenesis via a cross-talk with endothelial cells and reveal a novel component of the vesicular exocytic machinery in tumor microenvironment and tumor progression PMID: 28151721
- Results identify Rab37 as an additional component of the machinery governing exocytosis of beta-cells and suggest that impaired expression of this GTPase may contribute to defective insulin release in pre-diabetic and diabetic conditions. PMID: 23826383
- RAB37 regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 migration axis in vitro and in vivo and to suppress tumor metastasis. PMID: 25183545
- Rab37 mRNA was specifically expressed in some ESCC cell lines but its genetic polymorphisms were not associated with esophageal squamous cell carcinoma. PMID: 23372429
- Promoter/exon1 methylation is the predominant mechanism in down-regulation of the hRAB37, and can serve as a potential prediction biomarker of NSCLC progression. PMID: 18687502
- the TMEM22/RAB37 complex is likely to play a crucial role in growth of renal cell carcinoma PMID: 19148500
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亞細胞定位：Cytoplasmic vesicle.
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蛋白家族：Small GTPase superfamily, Rab family
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數據庫鏈接：
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