RAB11FIP5 Antibody

說明書

產品詳情

Uniprot No.：

Q9BXF6
基因名：

RAB11FIP5
別名：

GAF 1 antibody; Gaf-1 antibody; GAF1 antibody; gamma SNAP associated factor 1 antibody; Gamma-SNAP-associated factor 1 antibody; KIAA0857 antibody; Phosphoprotein pp75 antibody; pp75 antibody; RAB11 family interacting protein 5 (class I) antibody; Rab11 family-interacting protein 5 antibody; Rab11 FIP5 antibody; Rab11 interacting protein antibody; Rab11 interacting protein Rip11 antibody; Rab11-FIP5 antibody; Rab11-interacting protein Rip11 antibody; Rab11fip5 antibody; RFIP5_HUMAN antibody; RIP11 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human RAB11FIP5
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
基因功能參考文獻：
1. FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase. PMID: 24591568
2. FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells. PMID: 21969467
3. These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland. PMID: 20717956
4. analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ). PMID: 18384058
亞細胞定位：

Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein.
組織特異性：

Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
數據庫鏈接：

HGNC: 24845

OMIM: 605536

KEGG: hsa:26056

STRING: 9606.ENSP00000258098

UniGene: Hs.24557

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