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中文名稱：Pklr兔多克隆抗體
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貨號：CSB-PA018071LA01RA
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規格：￥440
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圖片：
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Western blot
All lanes: Pklr antibody at 2µg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 63, 59 kDa
Observed band size: 63 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Rattus norvegicus (Rat) Pklr Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：PklrPyruvate kinase PKLR antibody; EC 2.7.1.40 antibody; L-PK antibody; Pyruvate kinase isozymes L/R antibody
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宿主：Rabbit
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反應種屬：Rat, Human
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免疫原：Recombinant Rat Pyruvate kinase PKLR protein (1-574AA)
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免疫原種屬：Rattus norvegicus (Rat)
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標記方式：Non-conjugated
本頁面中的產品，Pklr Antibody (CSB-PA018071LA01RA)，的標記方式是Non-conjugated。對于Pklr Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays a key role in glycolysis.
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基因功能參考文獻：
- Studied the effect of the point mutations around this phosphorylation site on the catalytic properties of L-pyruvate kinase. PMID: 22878931
- c-Myc is required for the glucose-mediated induction of this metabolic enzyme. PMID: 12480946
- We observed that cystine inhibited the enzyme pyruvate kinase activity non-competitively in a dose- and time-dependent way. PMID: 15196592
- cooperative interaction between NF1 family members and HNF1alpha plays an important role in hepatic L-PK transcription PMID: 16204235
- Regulation of hepatic L-pyruvate kinase promoter composition and activity PMID: 16644726
- A novel chimeric promoter, consisting of a 1.6 kb glucose 6-phosphatase promoter and a segment of the regulatory element derived from the L-type pyruvate kinase promoter, was designed to provide strong and tight control of insulin expression in liver. PMID: 17160355
- Maximal glucose-induced expression of the L-PK gene in INS-1-derived 832/13 cells involves increased c-Myc abundance, recruitment of c-Myc, Max, and ChREBP to the promoter, and a glucose-stimulated increase in ChREBP transactivation. PMID: 17341548
- A detailed analysis of the molecular events of the insulin-independent glucose response of the liver-type pyruvate kinase (L-PK) gene was performed. PMID: 18468514
- cAMP and glucose signaling converge on a complex containing ChREBP, HNF4alpha, and CBP, and cAMP acts by disrupting this transcriptional complex assembled by glucose-derived signals PMID: 19406844
- Data show that glucose regulates acetylation and methylation of various histone residues at the L-PK gene promoter. PMID: 19631660
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蛋白家族：Pyruvate kinase family
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數據庫鏈接：
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