Pdk3 Antibody

產品詳情

產品名稱：

Rabbit anti-Mus musculus (Mouse) Pdk3 Polyclonal antibody
Uniprot No.：

Q922H2
基因名：

Pdk3
別名：

Pdk3 antibody; [Pyruvate dehydrogenase antibody; acetyl-transferring)] kinase isozyme 3 antibody; mitochondrial antibody; EC 2.7.11.2 antibody; Pyruvate dehydrogenase kinase isoform 3 antibody
宿主：

Rabbit
反應種屬：

Mouse, Human, Rat
免疫原：

Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (131-362AA)
免疫原種屬：

Mus musculus (Mouse)

標記方式：

Non-conjugated

本頁面中的產品，Pdk3 Antibody (CSB-PA852852LA01MO)，的標記方式是Non-conjugated。對于Pdk3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA852852LB01MO	Pdk3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA852852LC01MO	Pdk3 Antibody, FITC conjugated
Biotin	CSB-PA852852LD01MO	Pdk3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.
基因功能參考文獻：
1. demonstrate that the increased PDK3 activity in patient fibroblasts (PDK3(R158H)) leads to the attenuation of PDC through hyper-phosphorylation of E1 at selected serine residues PMID: 27388934
亞細胞定位：

Mitochondrion matrix.
蛋白家族：

PDK/BCKDK protein kinase family
數據庫鏈接：

KEGG: mmu:236900

STRING: 10090.ENSMUSP00000036604

UniGene: Mm.12775

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