Pcsk2 Antibody, FITC conjugated

^{Rare Species}

說明書

中文名稱：

Pcsk2兔多克隆抗體, FITC偶聯
貨號：

CSB-PA017642LC01RA
規格：

￥880
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Rattus norvegicus (Rat) Pcsk2 Polyclonal antibody
Uniprot No.：

P28841
基因名：

Pcsk2
別名：

Pcsk2 antibody; Nec-2 antibody; Nec2 antibody; Rpc2 antibody; Neuroendocrine convertase 2 antibody; NEC 2 antibody; EC 3.4.21.94 antibody; KEX2-like endoprotease 2 antibody; Prohormone convertase 2 antibody; Proprotein convertase 2 antibody; PC2 antibody
宿主：

Rabbit
反應種屬：

Rat
免疫原：

Recombinant Rat Neuroendocrine convertase 2 protein (109-637AA)
免疫原種屬：

Rattus norvegicus (Rat)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.
基因功能參考文獻：
1. The nutrient sensor sirtuin 1 regulates the production of CRH post-translationally by affecting PC2 post-translationally by affecting PC2. PMID: 26755731
2. The presence of PC and GOAT in the cells, as well as n-octanoic acid in the culture medium, was necessary to produce n-octanoyl ghrelin. PMID: 19628676
3. The prohormone convertase (PC) enzyme PC1 together with PC2 and PC5 may represent a redundant system to ensure production of biologically active cholecystokinin in rat brain PMID: 14608596
4. Leptin regulates hypothalamic Pcsk2 expression and requires prohormone processing into mature peptides. PMID: 15286802
5. study demonstrates abundant expression of PC2 mRNA in rat brain and shows that thyroid status regulated PC2 expression in the hypothalamus and cortex [PC2] PMID: 15585599
6. Expression levels of POMC processing enzymes prohormone convertases 1 and 2 (PC1/PC2) were not significantly affected by high dietary salt intake in either WKY or SP-SHR tissues. PMID: 17531155
7. our data anticipate the possibility that carboxypeptidase-E, prohormone convertase 1, and prohormone convertase 2 might be potential target for the maturation of somatostatin PMID: 17543468
8. PC1/PC3 and PC2 (specific to neural and endocrine cells) are absent in undifferentiated bone marrow stromal stem cells, their expression is initiated upon the induction of differentiation PMID: 17556096
9. brain ischemia attenuates PC2 and PC2-mediated neuropeptide processing. PMID: 19142196
10. PC2, CPE and preproNPY protein expression levels were compared among mature retina tissue, RGC-5 cells and its differentiated cells; differentiated cells or tissues had higher or highest PC2 activity PMID: 19428990
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亞細胞定位：

Cytoplasmic vesicle, secretory vesicle. Secreted.
蛋白家族：

Peptidase S8 family, Furin subfamily
數據庫鏈接：

KEGG: rno:25121

STRING: 10116.ENSRNOP00000007249

UniGene: Rn.89052

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