PSPH Antibody
-
中文名稱：PSPH兔多克隆抗體
-
貨號：CSB-PA018938ESR1HU
-
規格：￥440
-
圖片：
-
Western blot
All lanes: PSPH antibody at 3.81µg/ml
Lane 1: HL60 whole cell lysate
Lane 2: A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25 kDa
Observed band size: 25 kDa -
Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA018938ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018938ESR1HU at dilution of 1:100
-
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) PSPH Polyclonal antibody
-
Uniprot No.：
-
基因名：PSPH
-
別名：EC 3.1.3.3 antibody; L 3 phosphoserine phosphatase antibody; L-3-phosphoserine phosphatase antibody; O phosphoserine phosphohydrolase antibody; O-phosphoserine phosphohydrolase antibody; Phosphoserine phosphatase antibody; Phosphoserine phosphatase deficiency; included antibody; PSP antibody; PSPase antibody; Psph antibody; PSPHD antibody; SERB_HUMAN antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human Phosphoserine phosphatase protein (1-225AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA, WB, IHC
-
推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine (Probable).
-
基因功能參考文獻：
- PSPH expression is a novel biomarker for poor prognosis and could play an important role in tumor progression of colorectal cancer. PMID: 28476802
- We further uncovered that phosphoserine phosphatase (PSPH), the final rate-limiting enzyme of the SSP pathway, is critical for cMyc-driven cancer progression both in vitro and in vivo PMID: 25793315
- study of an intellectual disability family from Pakistan; identified a variant in PSPH: chr7:56088803C>T, NM_004577.3 c.103G>A; p.Ala35Thr (hg19) which segregated in homozygous form with the phenotype in both branches of the family PMID: 25080166
- phosphoserine phosphatase deficiency is associated with Neu-Laxova syndrome. PMID: 25152457
- status of PSPH in normal skin epidermis and skin tumors along with its sub-cellular localization in epidermal keratinocytes and its requirement for squamous cell carcinoma proliferation PMID: 21726982
- purification, crystallization and preliminary X-ray diffraction analysis PMID: 11752790
- description of the first crystal structures of the HPSP in complexes with the competitive inhibitor 2-amino-3-phosphonopropionic a PMID: 12213811
- human phosphoserine phosphatase structure now shows a sevenfold coordinated Ca(2+) ion in the active site that might explain the inhibitory effect of Ca(2+) on the enzyme PMID: 15291819
顯示更多
收起更多
-
相關疾病：Phosphoserine phosphatase deficiency (PSPHD)
-
亞細胞定位：Cytoplasm, cytosol.
-
蛋白家族：HAD-like hydrolase superfamily, SerB family
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
-
-
-
-
-
