PSG1 Antibody

說明書

中文名稱：

PSG1兔多克隆抗體
貨號：

CSB-PA018849ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018849ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA018849ESR1HU at dilution of 1:100

Immunoprecipitating PSG1 in A549 whole cell lysate
Lane 1: Rabbit control IgG instead of CSB-PA018849ESR1HU in A549 whole cell lysate. For western blotting, a HRP-conjµgated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-PA018849ESR1HU (8µg) + A549 whole cell lysate (500µg)
Lane 3: A549 whole cell lysate (10µg)
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PSG1 Polyclonal antibody
Uniprot No.：

P11464
基因名：

PSG1
別名：

B1G1 antibody; Carcinoembryonic antigen SG8 antibody; CD66 antigen-like family member F antibody; CD66f antibody; CD66f antigen antibody; CEA antibody; DHFRP2 antibody; Fetal liver non-specific cross-reactive antigen 1/2 antibody; FL-NCA-1/2 antibody; PBG 1 antibody; PBG1 antibody; Pregnancy specific B 1 glycoprotein antibody; Pregnancy specific beta 1 glycoprotein 1 antibody; Pregnancy specific beta 1 glycoprotein 2 antibody; Pregnancy specific beta 1 glycoprotein 7 antibody; Pregnancy specific beta 1 glycoprotein 8 antibody; Pregnancy specific beta 1 glycoprotein antibody; Pregnancy specific beta 1 glycoprotein C/D antibody; Pregnancy-specific beta-1 glycoprotein C/D antibody; Pregnancy-specific beta-1-glycoprotein 1 antibody; Pregnancy-specific glycoprotein 1 antibody; PS beta C/D antibody; PS-beta-C/D antibody; PS-beta-G-1 antibody; PSBG 1 antibody; PSBG 2 antibody; PSBG-1 antibody; PSBG1 antibody; PSBG2 antibody; PSG 1 antibody; PSG 2 antibody; PSG 8 antibody; PSG 95 antibody; PSG IIA d antibody; PSG1 antibody; PSG1_HUMAN antibody; PSG2 antibody; PSG8 antibody; PSG95 antibody; PSGGA antibody; PSGGB antibody; PSGIIA a antibody; PSGIIA antibody; PSGIIA b antibody; PSGIIA c antibody; SP 1 antibody; SP1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Pregnancy-specific beta-1-glycoprotein 1 protein (180-419AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IP

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IP	1:200-1:2000

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

基因功能參考文獻：
1. Inhibiting PSG1 can effectively reduce chemoresistance via a transforming growth factor-beta (TGF-beta)-related pathway in ER-negative breast cancer cells. PMID: 27653744
2. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-gamma. PMID: 27595833
3. Under conditions of directed induction of phenotypic changes in CD4(+) lymphocytes to regulatory T cells (Treg), pregnancy-specific at high concentrations (10 and 100 mug/mL) increased FOXP3 expression. The evaluation of the spontaneous expression level of FOXP3 mRNA showed that pregnancy-specific beta1-glycoprotein (1 and 100 mug/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4(+) lym... PMID: 27817017
4. results identify a non-placental site of PSG expression in the gut and associated tumors, with implications for determining whether PSGs have a role in tumor progression, and utility as tumor biomarkers. PMID: 26926266
5. the presence of GAGs on the surface of endothelial cells was required for the ability of PSG1 to induce tube formation PMID: 21193412
6. The aspartic acid at position 95 is not required for PSG1 activity but the amino acids implicated in the formation of a salt bridge within the N-domain are essential. PMID: 20335639
7. first trimester maternal serum marker of small-for-gestational age and preterm delivery PMID: 19911417
8. Human PSG1a induces alternative activation in human & mouse monocytes & suppresses the accessory-cell-dependent T-cell proliferation. PSG1a contributes to immunomodulation during pregnancy, with opposite effects on maternal innate & adaptative systems. PMID: 12223519
9. The differential expression of HLA-E and PSG1 in the sperm of fertile and infertile men is discussed. PMID: 18987160
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亞細胞定位：

Secreted.
蛋白家族：

Immunoglobulin superfamily, CEA family
數據庫鏈接：

HGNC: 9514

OMIM: 176390

KEGG: hsa:5669

STRING: 9606.ENSP00000244296

UniGene: Hs.709192

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