PRTFDC1 Antibody

中文名稱：

PRTFDC1兔多克隆抗體
貨號：

CSB-PA889092LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA889092LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA889092LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PRTFDC1 Polyclonal antibody
Uniprot No.：

Q9NRG1
基因名：

PRTFDC1
別名：

FLJ11888 antibody; HHGP antibody; OTTHUMP00000019332 antibody; Phosphoribosyl transferase domain containing 1 antibody; phosphoribosyltransferase domain containing protein 1 antibody; Phosphoribosyltransferase domain-containing protein 1 antibody; PRDC1_HUMAN antibody; prtfdc1 antibody; Uncharacterized protein PRTFDC1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Phosphoribosyltransferase domain-containing protein 1 (2-225AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，PRTFDC1 Antibody (CSB-PA889092LA01HU)，的標記方式是Non-conjugated。對于PRTFDC1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA889092LB01HU	PRTFDC1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA889092LC01HU	PRTFDC1 Antibody, FITC conjugated
Biotin	CSB-PA889092LD01HU	PRTFDC1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
基因功能參考文獻：
1. We found evidence for PRTFDC1 as a potential novel PTSD gene, a finding that awaits further replication. PMID: 25456346
2. These results demonstrate that PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. PMID: 21818316
3. The PRTFDC1 structure has been determined at 1.7 A resolution with bound GMP. The overall structure and GMP binding mode are very similar to that observed for HPRT. PMID: 21054786
4. epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PMID: 17599052
蛋白家族：

Purine/pyrimidine phosphoribosyltransferase family
數據庫鏈接：

HGNC: 23333

OMIM: 610751

KEGG: hsa:56952

STRING: 9606.ENSP00000318602

UniGene: Hs.405619

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