PRPF4 Antibody
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中文名稱：PRPF4兔多克隆抗體
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貨號：CSB-PA018768ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: PRPF4 antibody at 2.87µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 59 kDa
Observed band size: 59 kDa -
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA018768ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018768ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PRPF4 Polyclonal antibody
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Uniprot No.：
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基因名：PRPF4
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別名：hPrp4 antibody; HPRP4P antibody; PRP4 antibody; PRP4 homolog antibody; PRP4 pre mRNA processing factor 4 homolog (yeast) antibody; PRP4/STK/WD splicing factor antibody; PRP4_HUMAN antibody; Prp4p antibody; PRPF4 antibody; RP70 antibody; SNRNP60 antibody; U4/U6 small nuclear ribonucleoprotein Prp4 antibody; U4/U6 snRNP 60 kDa protein antibody; WD splicing factor Prp4 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human U4/U6 small nuclear ribonucleoprotein Prp4 protein (1-260AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
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基因功能參考文獻：
- The p.R192H variant of PRPF4 represents a functional null allele which compromises the function of the tri-snRNP, reinforcing the notion that this spliceosomal particle is of crucial importance in the physiology of the retina. PMID: 25383878
- PRPF4 missense mutations is associated with autosomal dominant retinitis pigmentosa. PMID: 24419317
- the requirement of enzymatic activity of PRP4 in regulating cancer cell growth and identified an array of potential novel substrates through orthogonal proteomics approaches PMID: 24003220
- interaction between Hprp3p and Hprp4p PMID: 11971898
- PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores. PMID: 17998396
- PRP-4 belongs to the serine/threonine protein kinase family, plays a role in pre-mRNA splicing and cell mitosis, and interacts with CLK1 PMID: 18687998
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相關疾?。?/div>Retinitis pigmentosa 70 (RP70)亞細胞定位：Nucleus. Nucleus speckle.數據庫鏈接：
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