PRMT8 Antibody
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中文名稱：PRMT8兔多克隆抗體
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貨號：CSB-PA018737GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：PRMT8
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別名：ANM8_HUMAN antibody; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 4 antibody; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4 antibody; HMT1 hnRNP methyltransferase like 3 antibody; HMT1 hnRNP methyltransferase like 4 antibody; HRMT1 L3 antibody; HRMT1 L4 antibody; HRMT1L 3 antibody; HRMT1L 4 antibody; HRMT1L3 antibody; HRMT1L4 antibody; prmt8 antibody; Protein arginine N methyltransferase 4 antibody; Protein arginine N methyltransferase 8 antibody; Protein arginine N-methyltransferase 8 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human PRMT8
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.
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基因功能參考文獻：
- PRMT8 in human embryonic stem cells plays an important role not only in maintaining pluripotency but also in controlling mesodermal differentiation. PMID: 28543863
- Biochemical, biophysical and mutagenesis experiments demonstrated that hPRMT8 forms an octamer in solution. PMID: 26876602
- Mutational defects in PRMT8 is not the cause of frontotemporal lobar degeneration. PMID: 23635657
- automethylation of the N terminus likely regulates PRMT8 activity by decreasing the affinity of the enzyme for AdoMet PMID: 23946480
- wild type FUS (FUS-WT) specifically interacts with protein arginine methyltransferases 1 and 8 (PRMT1 and PRMT8) and undergoes asymmetric dimethylation PMID: 23620769
- PRMT8 is an active arginine methyltransferase that is membrane-associated and tissue-specific PMID: 16051612
- PRMT8 N-terminal domain may function as an autoregulator that may be displaced by interaction with one or more physiological inducers. PMID: 17925405
- The interaction between PRMT8 and the EWS protein was charcterized. PMID: 18320585
- EWS is a substrate for PRMT8, as efficient as for PRMT1 PMID: 18698489
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亞細胞定位：Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family, PRMT8 subfamily
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組織特異性：Brain-specific.
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數據庫鏈接：
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