PPP2R5D Antibody
-
中文名稱：PPP2R5D兔多克隆抗體
-
貨號(hào)：CSB-PA143410
-
規(guī)格：￥2024
-
圖片：
-
Western blot analysis of extracts from HuvEc cells and Jurkat cells, using PPP2R5D antibody.
-
-
其他：
產(chǎn)品詳情
-
產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) PPP2R5D Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
宿主：Rabbit
-
反應(yīng)種屬：Human
-
免疫原：Synthesized peptide derived from internal of Human PPP2R5D.
-
免疫原種屬：Homo sapiens (Human)
-
克隆類型：Polyclonal
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA,WB
-
推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
-
基因功能參考文獻(xiàn)：
- Mutations in PPP2R5D are genetic cause of intellectual disability. PMID: 26576547
- MiR-9 regulates GR signaling and steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity. PMID: 25772595
- Mutant B56delta was A and C binding-deficient, while mutant Aalpha subunits bound B56delta well but were unable to bind C PMID: 26168268
- PP2A-B56delta is the single most significant contributor, of the PP2A holoenzyme subunits, to BubR1 and Bub1 kinetochore localization. PMID: 25246613
- Protein kinase A mediated activation of protein phosphatase 2A is enabled by PPP2R5D phosphorylation, which modulates the affinity of the protein phosphatase 2A holoenzyme to its physiological substrates. PMID: 20423611
- Data show that the protein phosphatase 2A subunit B56delta specifically interacts with HAND1 and -2, but not other basic helix-loop-helix proteins. PMID: 14636580
- Gonadotropin-releasing hormone (GnRH) affects the membrane protein phosphatase 2A-associated apoptosis and the enzyme activity in ovarian cancer cells. PMID: 15809743
- PP2A:B56delta as a key upstream regulator of Cdk1 activity upon exit from mitosis PMID: 18056802
顯示更多
收起更多
-
相關(guān)疾病：Mental retardation, autosomal dominant 35 (MRD35)
-
亞細(xì)胞定位：Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis.
-
蛋白家族：Phosphatase 2A regulatory subunit B56 family
-
組織特異性：Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
-
數(shù)據(jù)庫鏈接：
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
