POLR2D Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) POLR2D Polyclonal antibody
Uniprot No.：

O15514
基因名：

POLR2D
別名：

DNA directed RNA polymerase II 16 kDa polypeptide antibody; DNA directed RNA polymerase II subunit D antibody; DNA directed RNA polymerase II subunit RPB4 antibody; DNA-directed RNA polymerase II 16 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit D antibody; DNA-directed RNA polymerase II subunit rpb4 antibody; HSRBP4 antibody; HSRPB4 antibody; polr2d antibody; polymerase RNA II DNA directed polypeptide D antibody; RBP4 antibody; RNA polymerase II 16 kDa subunit antibody; RNA polymerase II subunit B4 antibody; RNA polymerase II subunit D antibody; RNA polymerase II subunit hsRBP4 antibody; RPB16 antibody; RPB4_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，POLR2D Antibody (CSB-PA018331LA01HU)，的標記方式是Non-conjugated。對于POLR2D Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA018331LB01HU	POLR2D Antibody, HRP conjugated	ELISA
FITC	CSB-PA018331LC01HU	POLR2D Antibody, FITC conjugated
Biotin	CSB-PA018331LD01HU	POLR2D Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.
基因功能參考文獻：
1. Identification of the RNA binding region of Rpb4. PMID: 16282592
亞細胞定位：

Nucleus.
蛋白家族：

Eukaryotic RPB4 RNA polymerase subunit family
數據庫鏈接：

HGNC: 9191

OMIM: 606017

KEGG: hsa:5433

STRING: 9606.ENSP00000272645

UniGene: Hs.715348

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