POC5 Antibody

中文名稱：

POC5兔多克隆抗體
貨號：

CSB-PA843309LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA843309LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) POC5 Polyclonal antibody
Uniprot No.：

Q8NA72
基因名：

POC5
別名：

C5orf37 antibody; Centrosomal protein POC5 antibody; FLJ35779 antibody; hPOC5 antibody; MGC120442 antibody; MGC120443 antibody; MGC120444 antibody; OTTHUMP00000222116 antibody; OTTHUMP00000222453 antibody; Poc5 antibody; POC5 centriolar protein antibody; POC5 centriolar protein homolog (Chlamydomonas) antibody; POC5 centriolar protein homolog antibody; POC5_HUMAN antibody; Protein of centriole 5 antibody; Proteome of centriole 5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Centrosomal protein POC5 protein (373-485AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，POC5 Antibody (CSB-PA843309LA01HU)，的標記方式是Non-conjugated。對于POC5 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA843309LB01HU	POC5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA843309LC01HU	POC5 Antibody, FITC conjugated
Biotin	CSB-PA843309LD01HU	POC5 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Essential for the assembly of the distal half of centrioles, required for centriole elongation.
基因功能參考文獻：
1. Common variant rs6892146 of POC5 is associated with the development of adolescent idiopathic scoliosis in the Chinese population. PMID: 29189569
2. Depletion of CEP295 blocks the incorporation of POC5 and POC1B into the distal portion of centrioles and suppresses the post-translational modification of centriolar microtubules . Our study thus uncovers a new role for CEP295 during centriole elongation. PMID: 27185865
3. Mutations in the POC5 gene contribute to the occurrence of idiopathic scoliosis. PMID: 25642776
4. Data indicate that overexpression of the centrin interactor POC5 leads to the assembly of linear, centrin-dependent structures. PMID: 23844208
5. hPOC5, a conserved centrin-binding protein that contains Sfi1p-like repeats is characterized. PMID: 19349582
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亞細胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized to the distal portion of centrioles.
蛋白家族：

POC5 family
數據庫鏈接：

HGNC: 26658

OMIM: 617880

KEGG: hsa:134359

STRING: 9606.ENSP00000410216

UniGene: Hs.432726

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