PMS1 Antibody
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中文名稱：PMS1兔多克隆抗體
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貨號：CSB-PA018245GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：PMS1
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別名：DNA mismatch repair protein PMS1 antibody; FLJ98259 antibody; HNPCC3 antibody; hPMS1 antibody; Human homolog of yeast mutL antibody; Mismatch repair gene PMSL1 antibody; pms1 antibody; PMS1 postmeiotic segregation increased 1 (S. cerevisiae) antibody; PMS1 postmeiotic segregation increased 1 antibody; PMS1 protein homolog 1 antibody; PMS1_HUMAN antibody; PMSL1 antibody; Rhabdomyosarcoma antigen MU RMS 40.10B antibody; Rhabdomyosarcoma antigen MU RMS 40.10E antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human PMS1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Probably involved in the repair of mismatches in DNA.
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基因功能參考文獻(xiàn)：
- Genome-wide association study identifies variants in PMS1 associated with serum ferritin in a Chinese population. PMID: 25162662
- These studies establish that the Mlh1-Pms1 endonuclease is required for MMR in a previously uncharacterized Exo1-independent MMR pathway. PMID: 24204293
- PMS1 is most likely deregulated by post-transcriptional modification in oral squamous cell carcinoma. PMID: 23608172
- hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA PMID: 11809883
- The expression of hMLH1 and hPMS1 was significantly low in some large B-cell lymphomas and in mantle cell lymphomas of the blastoid type and may be related to the natural history of these neoplasms. PMID: 11999575
- Data show that DNA damage induces the accumulation of hPMS1, hPMS2, and hMLH1 through ataxia-telangiectasia-mutated (ATM)-mediated protein stabilization. PMID: 15226443
- hPMS1 may be useful as CD4+ helper T cell antigens for immunotherapy of pancreatic cancer patients. PMID: 15856462
- In pstreplicative mismatch repair, this protein interacts wiwth MutL protein. PMID: 17148452
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亞細(xì)胞定位：Nucleus.
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蛋白家族：DNA mismatch repair MutL/HexB family
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數(shù)據(jù)庫鏈接：
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