PLPBP Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PLPBP Polyclonal antibody
Uniprot No.：

O94903
基因名：

PLPBP
別名：

FLJ11861 antibody; Proline synthase co-transcribed bacterial homolog protein antibody; Proline synthetase co transcribed bacterial homolog antibody; Proline synthetase co transcribed homolog (bacterial) antibody; PROSC antibody; PROSC_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Pyridoxal phosphate homeostasis protein (1-275AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.
基因功能參考文獻：
1. We therefore confirm PROSC as a novel gene for vitamin-B6-dependent epilepsy and delineate a non-specific plasma vitamin B6 profile under pyridoxine treatment. PMID: 28391250
2. Exploiting the universality of the Synechococcus elongatus COG0325 (PiPY) functions, it has been used in site-directed mutagenesis studies to shed light on disease causation by epilepsy-associated mutations in the human COG0325 gene PROSC. PMID: 28914444
3. studies suggest that PROSC is involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate, supplying this cofactor to apoenzymes while minimizing any toxic side reactions PMID: 27912044
相關疾病：

Epilepsy, early-onset, vitamin B6-dependent (EPVB6D)
蛋白家族：

Pyridoxal phosphate-binding protein YggS/PROSC family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 9457

OMIM: 604436

KEGG: hsa:11212

STRING: 9606.ENSP00000333551

UniGene: Hs.304792

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