PLK5 Antibody

說明書

中文名稱：

PLK5兔多克隆抗體
貨號：

CSB-PA003821
規格：

￥1090
圖片：
Western Blot analysis of COLO205 cells using PLK-5 Polyclonal Antibody

Western Blot analysis of Jurkat K562 NIH-3T3 cells using PLK-5 Polyclonal Antibody
其他：

產品詳情

Uniprot No.：

Q496M5
基因名：

PLK5
別名：

PLK5 antibody; PLK5P antibody; FG060302 antibody; Inactive serine/threonine-protein kinase PLK5 antibody; Polo-like kinase 5 antibody; PLK-5 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human PLK-5.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
基因功能參考文獻：
1. we report a three-nucleotide deletion near the C-region of Plk5 that is specifically associated with the lymphatic metastasis in patients with clear cell renal cell carcinoma PMID: 26908440
2. The human polo-like kinase 5 gene is significantly silenced in astrocytoma and glioblastoma multiforme by promoter hypermethylation, suggesting a tumor suppressor function for this gene. PMID: 21245385
亞細胞定位：

Nucleus, nucleolus. Cytoplasm.
蛋白家族：

Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily
組織特異性：

Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in t
數據庫鏈接：

HGNC: 27001

KEGG: hsa:126520

STRING: 9606.ENSP00000466248

UniGene: Hs.195352

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