PKD1L3 Antibody, Biotin conjugated
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中文名稱：PKD1L3兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA767197LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PKD1L3 Polyclonal antibody
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Uniprot No.：
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基因名：PKD1L3
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別名：PKD1L3 antibody; Polycystic kidney disease protein 1-like 3 antibody; PC1-like 3 protein antibody; Polycystin-1L3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Polycystic kidney disease protein 1-like 3 protein (22-194AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
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基因功能參考文獻：
- our study identified C1 as the first PKD2L1 domain essential for both PKD2L1 trimerization and channel function, and suggest that PKD2L1 and PKD2L1/PKD1L3 channels share the PKD2L1 trimerization process. PMID: 25820328
- functions as a channel-forming subunit in an acid-sensing heteromeric complex formed by PKD1L3 and TRPP3 PMID: 23212381
- Among the three gustatory regions innervated by peripheral gustatory neurons in the geniculate ganglion, transgenic Pkd1l3 is expressed in the foliate papillae, not in the fungiform papillae or palate. PMID: 21883212
- Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
- the PKD2L1-PKD1L3 complex is involved in acid sensing in vivo PMID: 20406802
- genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129
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亞細胞定位：Cell membrane; Multi-pass membrane protein. Note=Interaction with PKD2L1 is required for localization to the cell membrane.
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蛋白家族：Polycystin family
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組織特異性：Highly expressed in placenta, weakly in heart and lung.
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數據庫鏈接：
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