PIGR Antibody, FITC conjugated

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說明書

產品詳情

產品名稱：

Rabbit anti-Bovine PIGR Polyclonal antibody
Uniprot No.：

P81265
基因名：

PIGR
別名：

PIGR antibody; Polymeric immunoglobulin receptor antibody; PIgR antibody; Poly-Ig receptor) [Cleaved into: Secretory component] antibody
宿主：

Rabbit
反應種屬：

Bovine
免疫原：

Recombinant Bovine Polymeric immunoglobulin receptor protein (399-599AA)
免疫原種屬：

Bovine
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.; Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens. On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
基因功能參考文獻：
1. This study evaluated the production of polymeric immunoglobulin receptor and immunoglobulin A in the salivary glands of cattle. PMID: 23395346
亞細胞定位：

[Polymeric immunoglobulin receptor]: Cell membrane; Single-pass type I membrane protein.; [Secretory component]: Secreted.
組織特異性：

Found in mammary gland, jejunum, lung, kidney and small intestine.
數據庫鏈接：

KEGG: bta:281401

STRING: 9913.ENSBTAP00000026377

UniGene: Bt.4695

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