PIGL Antibody

中文名稱：

PIGL兔多克隆抗體
貨號：

CSB-PA897465LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA897465LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA897465LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PIGL Polyclonal antibody
Uniprot No.：

Q9Y2B2
基因名：

PIGL
別名：

N acetylglucosaminylphosphatidylinositol deacetylase antibody; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase antibody; Phosphatidylinositol glycan anchor biosynthesis class L antibody; Phosphatidylinositol glycan class L antibody; Phosphatidylinositol-glycan biosynthesis class L protein antibody; PIG-L antibody; Pigl antibody; PIGL_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase protein (23-252AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，PIGL Antibody (CSB-PA897465LA01HU)，的標記方式是Non-conjugated。對于PIGL Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA897465LB01HU	PIGL Antibody, HRP conjugated	ELISA
FITC	CSB-PA897465LC01HU	PIGL Antibody, FITC conjugated
Biotin	CSB-PA897465LD01HU	PIGL Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
基因功能參考文獻：
1. c.336-2A>G variant in PIGL associated with developmental disorder resulted in exon skipping. PMID: 28327575
2. these findings indicate that patients with a clinical diagnosis of CHIME syndrome and a single identifiable mutation in PIGL warrant further investigation for copynumber changes involving PMID: 28371479
3. fd hrhr rt eruj jej PMID: 25706356
4. Whole-exome sequencing on five previously reported CHIME cases identified PIGL (N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase) as required for glycosylphosphatidylinositol anchor formation. PMID: 22444671
相關疾病：

Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation and ear anomalies syndrome (CHIME)
亞細胞定位：

Endoplasmic reticulum membrane; Single-pass membrane protein.
蛋白家族：

PIGL family
數據庫鏈接：

HGNC: 8966

OMIM: 280000

KEGG: hsa:9487

STRING: 9606.ENSP00000225609

UniGene: Hs.499793

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