PHKA1 Antibody
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中文名稱：PHKA1兔多克隆抗體
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貨號：CSB-PA566650
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規格：￥2024
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圖片：
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Western blot analysis of extracts from Jurkat cells and COLO205 cells, using KPB1/2 antibody. -
Immunofluorescence analysis of HeLa cells, using KPB1/2 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PHKA1 Polyclonal antibody
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Uniprot No.：
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基因名：
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from internal of Human KPB1/2.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 IF 1:100-1:500 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
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基因功能參考文獻：
- muscle PHKA deficiency may present as an almost asymptomatic condition, despite a mild impairment of muscle PMID: 22238410
- alpha- and beta-subunits possess amino-terminal glucoamylase-like domains and suggests that they might possess a previously overlooked amylase activity PMID: 12876330
- X-linked PHK deficiency causes a mild metabolic myopathy with blunted muscle glycogen breakdown and impaired lactate production during dynamic exercise, which impairs oxidative capacity only marginally PMID: 18401027
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相關疾病：Glycogen storage disease 9D (GSD9D)
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亞細胞定位：Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Phosphorylase b kinase regulatory chain family
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組織特異性：Muscle specific. Isoform 1 is predominant in vastus lateralis muscle. Isoform 2 predominates slightly in heart, and it predominates clearly in the other tissues tested.
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數據庫鏈接：
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