PHAX Antibody
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中文名稱：PHAX兔多克隆抗體
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貨號：CSB-PA863999LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: A549 whole cell lysate
All lanes: PHAX antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 45 kDa
Observed band size: 45 kDa -
Immunofluorescent analysis of Hela cells using CSB-PA863999LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PHAX Polyclonal antibody
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Uniprot No.：
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基因名：PHAX
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別名：FLJ13193 antibody; PHAX antibody; PHAX_HUMAN antibody; Phosphorylated adapter RNA export protein antibody; Phosphorylated adaptor for RNA export antibody; RNA U small nuclear RNA export adapter protein antibody; RNA U; small nuclear RNA export adapter (phosphorylation regulated) antibody; RNUXA antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Phosphorylated adapter RNA export protein (6-243AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，PHAX Antibody (CSB-PA863999LA01HU)，的標記方式是Non-conjugated。對于PHAX Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IF 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner. Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.
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基因功能參考文獻：
- PHAX RNA-binding domain mediates auxiliary RNA contracts with small nuclear and mall nucleolar RNA substrates. PMID: 20430857
- PHAX and CRM1 have roles in transporting U3 snoRNA to nucleoli PMID: 15574332
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亞細胞定位：Nucleus, nucleoplasm. Nucleus, Cajal body. Cytoplasm.
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蛋白家族：PHAX family
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數據庫鏈接：
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