PGD Antibody
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中文名稱：PGD兔多克隆抗體
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貨號：CSB-PA01155A0Rb
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規格：￥440
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圖片：
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Western blot
All lanes: PGD antibody at 2µg/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 54, 52 kDa
Observed band size: 54 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PGD Polyclonal antibody
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Uniprot No.：
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基因名：PGD
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別名：0610042A05Rik antibody; 6 phosphogluconate dehydrogenase; decarboxylating antibody; 6-phosphogluconate dehydrogenase antibody; 6PGD antibody; 6PGD_HUMAN antibody; AU019875 antibody; C78335 antibody; decarboxylating antibody; OTTMUSP00000011754 antibody; Pgd antibody; Phosphogluconate dehydrogenase antibody; RP23-249G3.4 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human 6-phosphogluconate dehydrogenase, decarboxylating protein (4-483AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，PGD Antibody (CSB-PA01155A0Rb)，的標記方式是Non-conjugated。對于PGD Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
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基因功能參考文獻：
- identified that 6-phosphogluconate dehydrogenase (6PGD) is critically involved in the development of anaplastic thyroid cancer (ATC) resistance to doxorubicin. 6PGD inhibition disrupts metabolic reprogramming in doxorubicin-resistant ATC cells. PMID: 29534964
- Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1-AMPK signalling. PMID: 26479318
- copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues PMID: 24125036
- Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells. PMID: 25042803
- Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation. PMID: 23973484
- Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence PMID: 22677172
- Data suggest that the affinity of Nox2 for NADPH is increased in the presence of 6PGDH on cell stimulation. PMID: 21444627
- Hsa-miR-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. PMID: 20675101
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亞細胞定位：Cytoplasm.
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蛋白家族：6-phosphogluconate dehydrogenase family
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數據庫鏈接：
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