PEBP4 Antibody, Biotin conjugated
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中文名稱：PEBP4兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA857025LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PEBP4 Polyclonal antibody
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Uniprot No.：
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基因名：PEBP4
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別名：PEBP4 antibody; CORK1 antibody; UNQ1933/PRO4408 antibody; Phosphatidylethanolamine-binding protein 4 antibody; PEBP-4 antibody; hPEBP4 antibody; Protein cousin-of-RKIP 1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Phosphatidylethanolamine-binding protein 4 protein (23-227AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Promotes AKT phosphorylation, suggesting a possible role in the PI3K-AKT signaling pathway.
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基因功能參考文獻：
- PEBP4 was associated with the development and invasion of gastric cancer cells through activation of the PI3K/Akt signaling pathway PMID: 28193908
- knockdown of PEBP4 inhibited hypoxia-induced epithelial-to-mesenchymal transition in prostate cancer cells. PMID: 27261570
- this study suggested that PEBP4 might promote the progression of pancreatic ductal adenocarcinoma PMID: 26311050
- Increased expression of phosphatidylethanolamine-binding protein 4 strongly associates with gliomas grade. PMID: 26725095
- PEBP4 is a secreted protein and has multiple functions, including a role in Akt phosphorylation. PMID: 27033522
- Increased miR-15b expression in lung adenocarcinoma patients treated with cisplatin-based chemotherapy was correlated with low expression of PEBP4, decreased sensitivity to cisplatin and poor prognosis. PMID: 25721211
- concluded that hPEBP4, specifically expressed in rectal cancer cells, is associated with radioresistance of rectal cancer PMID: 24594691
- overexpression of PEBP4, which we show to be a target of miR-34a, reduces the sensitivity of lung cancer cells to cisplatin PMID: 25038915
- in human breast cancer hPEBP4 is a novel and clinically relevant metastasis accelerator gene PMID: 24276246
- Human PEBP4 expression correlates negatively with estrogen and progesterone receptors in endometrial carcinoma. PMID: 23818363
- hPEBP4 knockdown potentiated the chemosensitization of the rituximab in B-cell lymphoma cells by regulating the expression of Bcl-xl, Cycline E, p21(waf/cip1) and p53 and the activation of caspase-3 and caspase-9. PMID: 23451095
- the independent predictive values of hPEBP4 in response of rectal cancer to preoperative radiotherapy, are reported. PMID: 22801881
- PEBP4 enhanced cell proliferation and invasion ability and inhibited apoptosis. Decreased PEBP4 expression may play a role in the reduced invasion ability and increased apoptosis of the human non-small cell lung cancer cell line HCC827. PMID: 22983920
- PEBP4 over-expression may promote the invasion and metastasis of non-small cell lung cancer. PMID: 22076923
- The over-expression of PEBP4 protein may be related to the tumorigenesis, development, metastasis, and invasion of colorectal cancer. PMID: 22125029
- Data show that PEBP4 protein overexpression was associated with the occurrence, invasion, and metastasis of lung squamous cell carcinoma. PMID: 21887552
- hPEBP4 inhibits proteasome-dependent ERalpha degradation through the Src pathway. PMID: 20460377
- hPEBP4 promotes cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK, and PE externalization. PMID: 15302887
- Silencing of hPEBP4, an important potential target, may be a promising approach for the treatment of ovarian cancer. PMID: 16865237
- Data show that PEBP4 participates in the control of muscle cell differentiation by modulating the activity of MEK and ERK. PMID: 19197339
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亞細胞定位：Secreted.
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蛋白家族：Phosphatidylethanolamine-binding protein family
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數據庫鏈接：
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