PDXK Antibody
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中文名稱：PDXK兔多克隆抗體
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貨號：CSB-PA017748GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：PDXK
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別名：pdxK antibody; PDXK_HUMAN antibody; PKH antibody; PNK antibody; Pyridoxal kinase antibody; Pyridoxamine kinase antibody; Pyridoxine kinase antibody; Pyridoxine kinase; antibody; Vitamin B6 kinase antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human PDXK
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.
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基因功能參考文獻：
- The affected pyridoxine metabolism is discussed as an inborn genetic trait in epilepsy in general, rather than a specific sign of pyridoxine-dependent epilepsy solely. PMID: 22647618
- The pyridoxal kinase showed decreased levels and was highly carbonylated in the gene-on mice PMID: 20639122
- This study identified a DNA variant (rs2010795) in PDXK associated with an increased risk of PD in the German cohort This association was confirmed in the British and Italian cohorts individually and reached a combined value. PMID: 20035503
- Pyridoxal kinase expression was compared in fetal Down syndrome (DS) brain and controls; PDXK levels were found to be similar. PMID: 15082224
- A promoter mutation with potential erythroid-specific properties that could be the basis of a novel mechanism of controlling cell-specific decreased activity of an essential enzyme in erythrocytes. PMID: 16704963
- The crystal structure of the MgATP complex also reveals Mg(2+) and Na(+) acting in tandem to anchor the ATP at the active site of pyridoxal kinase. PMID: 17766369
- These results document the role of Asp235 in PL kinase activity. PMID: 19351586
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亞細胞定位：Cytoplasm, cytosol.
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蛋白家族：Pyridoxine kinase family
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組織特異性：Ubiquitous. Highly expressed in testis.; [Isoform 3]: In adult testis and spermatozoa.
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數據庫鏈接：
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