PDE6A Antibody
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中文名稱：PDE6A兔多克隆抗體
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貨號：CSB-PA2109ESR1HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA2109ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA2109ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PDE6A Polyclonal antibody
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Uniprot No.：
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基因名：PDE6A
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別名：5''-cyclic phosphodiesterase subunit alpha antibody; CGPR A antibody; GMP PDE alpha antibody; GMP-PDE alpha antibody; PDE 6 alpha antibody; PDE 6A antibody; PDE V B1 antibody; PDE V-B1 antibody; PDE6A antibody; PDE6A_HUMAN antibody; PDEA antibody; Phosphodiesterase 6 alpha antibody; Phosphodiesterase 6A alpha subunit antibody; Phosphodiesterase 6A antibody; Phosphodiesterase 6A cGMP specific rod alpha antibody; Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha antibody; Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit antibody; Rod cGMP-specific 3'' antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Rod cGMP-specific 3\',5\'-cyclic phosphodiesterase subunit alpha protein (656-860AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：This protein participates in processes of transmission and amplification of the visual signal.
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基因功能參考文獻：
- this is the first phenotypic description of arRP due to homozygous IVS6+1G>A mutations in PDE6A and these seem here to be associated with severe RP leading to early extinction of rod responses as well as reduced macular function. PMID: 27820873
- report two splice acceptor site variations in PDE6A in consanguineous Pakistani families who manifested cardinal symptoms of autosomal recessive retinitis pigmentosa PMID: 26321862
- analysis of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 and PDE6 PMID: 23033484
- the p.Val685Met mutation in PDE6A causes retinal degeneration in humans PMID: 21039428
- Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent. PMID: 20940301
- full transcriptional activity of the PDE6A gene requires both Nrl and Crx PMID: 15001570
- Homozygous single base pair change; c.889C->T, single base pair insertion; c.2218-2219insT, and single base pair substitution in the splice acceptor site; IVS10-2A->G in each of three families. PMID: 17110911
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相關疾病：Retinitis pigmentosa 43 (RP43)
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亞細胞定位：Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Cyclic nucleotide phosphodiesterase family
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數據庫鏈接：
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