PASD1 Antibody, FITC conjugated
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中文名稱(chēng)：PASD1兔多克隆抗體, FITC偶聯(lián)
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貨號(hào)：CSB-PA816882LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱(chēng)：Rabbit anti-Homo sapiens (Human) PASD1 Polyclonal antibody
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Uniprot No.：
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基因名：PASD1
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別名：Cancer/testis antigen 63 antibody; CT63 antibody; OX-TES-1 antibody; PAS domain containing 1 antibody; PAS domain-containing protein 1 antibody; PASD1 antibody; PASD1_HUMAN antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Circadian clock protein PASD1 protein (301-600AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類(lèi)型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點(diǎn)詳情
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功能：Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed.
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基因功能參考文獻(xiàn)：
- PASD1 serves as a critical nuclear positive regulator of STAT3-mediated gene expression and tumorigenesis. PMID: 26892021
- PASD1 is a circadian bHLH-PAS paralog repressor of CLOCK protein expression. PMID: 25936801
- PASD1-derived epitopes are both efficiently and selectively processed and presented by native human multiple myeloma cells as cancer vaccines. PMID: 20861911
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亞細(xì)胞定位：[Isoform 1]: Nucleus.; [Isoform 2]: Nucleus.
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組織特異性：Testis-specific. Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widesp
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數(shù)據(jù)庫(kù)鏈接：
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