PADI3 Antibody, HRP conjugated
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中文名稱：PADI3兔多克隆抗體, HRP偶聯
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貨號：CSB-PA891552LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PADI3 Polyclonal antibody
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Uniprot No.：
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基因名：PADI3
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別名：PADI3 antibody; PADI3_HUMAN antibody; PDI3 antibody; Peptidyl arginine deiminase; type III antibody; Peptidylarginine deiminase III antibody; Protein arginine deiminase type 3 antibody; Protein arginine deiminase type III antibody; Protein-arginine deiminase type III antibody; Protein-arginine deiminase type-3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Protein-arginine deiminase type-3 protein (1-664AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the deimination of arginine residues of proteins.
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基因功能參考文獻：
- The two enzymes PADI3 and TGM3, responsible for posttranslational protein modifications, and their target structural protein TCHH are all involved in hair shaft formation. PMID: 27866708
- Crystals of PAD3 obtained using polyethylene glycol 400 as a precipitant diffracted to 2.95 A resolution using synchrotron radiation PMID: 22684066
- PAD3 is co-located with filaggrin within the filamentous matrix of the deeper corneocytes where the protein is deiminated. PMID: 16091842
- PADI3 expression is driven by Sp1/Sp3 and NF-Y binding to the promoter region PMID: 16671893
- cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3) PMID: 18083705
- Peptidylarginine deiminase Intergenic Enhancer is a strong enhancer of the PADI3 promoter in Ca2+-differentiated epidermal keratinocytes, and requires bound PMID: 18923650
- These results reveal the molecular bases of the expression specificity of PADI1 and PADI3 during keratinocyte differentiation through a long-range enhancer and support a model of PADI gene regulation depending on c-Jun-JunD competition. PMID: 18952102
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相關疾病：Uncombable hair syndrome 1 (UHS1)
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亞細胞定位：Cytoplasm.
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蛋白家族：Protein arginine deiminase family
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組織特異性：Hair follicles, and epidermis at very low levels.
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數據庫鏈接：
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