P4hb Antibody
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中文名稱：P4hb兔多克隆抗體
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貨號：CSB-PA017342YA01MO
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規格：￥440
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其他：
產品詳情
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產品名稱：Rabbit anti-Mus musculus (Mouse) P4hb Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：P4hb antibody; Pdia1Protein disulfide-isomerase antibody; PDI antibody; EC 5.3.4.1 antibody; Cellular thyroid hormone-binding protein antibody; Endoplasmic reticulum resident protein 59 antibody; ER protein 59 antibody; ERp59 antibody; Prolyl 4-hydroxylase subunit beta antibody; p55 antibody
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宿主：Rabbit
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反應種屬：Mouse
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免疫原：Recombinant Mouse Protein disulfide-isomerase protein (20-509AA)
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免疫原種屬：Mus musculus (Mouse)
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標記方式：Non-conjugated
本頁面中的產品，P4hb Antibody (CSB-PA017342YA01MO)，的標記方式是Non-conjugated。對于P4hb Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
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基因功能參考文獻：
- Unfolded protein response caused by protein misfolding, may lead to PDI-dependent NOX activation and contribute to neurotoxicity in neurodegenerative diseases including ALS. PMID: 23118353
- PDI from endothelial cells is required for fibrin generation in vivo. PMID: 20668226
- Protein disulfide isomerase (PDI) on the platelet surface is recognized by anti-dengue virus NS1 antibodies. PMID: 19822367
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亞細胞定位：Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome. Cell membrane; Peripheral membrane protein.
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蛋白家族：Protein disulfide isomerase family
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數據庫鏈接：
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