P Antibody, HRP conjugated

^{Rare Species}

說明書

產品詳情

產品名稱：

Rabbit anti-Hepatitis B virus genotype A2 subtype adw2 P Polyclonal antibody
Uniprot No.：

P17100
基因名：

P
別名：

PProtein P [Includes: DNA-directed DNA polymerase antibody; EC 2.7.7.7); RNA-directed DNA polymerase antibody; EC 2.7.7.49); Ribonuclease H antibody; EC 3.1.26.4)] antibody
宿主：

Rabbit
反應種屬：

Hepatitis B virus genotype A2 subtype adw2
免疫原：

Recombinant Hepatitis B virus genotype A2 subtype adw2 Protein P protein (349-692AA)
免疫原種屬：

Hepatitis B virus genotype A2 subtype adw2
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
蛋白家族：

Hepadnaviridae P protein family

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