Ovotransferrin Antibody, FITC conjugated

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說明書

中文名稱：

Ovotransferrin兔多克隆抗體, FITC偶聯
貨號：

CSB-PA00390G0Rb
規格：

￥880
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Chicken N/A Polyclonal antibody
Uniprot No.：

P02789
基因名：

N/A
別名：

Ovotransferrin antibody; Allergen Gal d III antibody; Conalbumin antibody; Serum transferrin antibody; allergen Gal d 3 antibody
宿主：

Rabbit
反應種屬：

Chicken
免疫原：

Chicken Ovotransferrin (Native Protein)
免疫原種屬：

Chicken
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. There are two forms of hen transferrin, ovotransferrin, found in the ovoducts and, serum transferrin, secreted by the liver. Serum transferrin may also have a role in stimulating cell proliferation and is regulated by iron levels. Ovotransferrin has a bacteriostatic function and, is not controlled by iron levels.
基因功能參考文獻：
1. unfolding pathway and conformational stability of conalbumin PMID: 21833676
2. glycosylation of fetal & hen ovotransferrin differs; hypothesized to alter ovotransferrin recognition by carbohydrate binding lectins PMID: 7881176
3. studied the carbohydrate and amino acid compositions of the ovotransferrin glycopeptides PMID: 574451
4. The exon structure of the ovotransferrin gene confirms the duplication event to produce two homologous domains that make up ovotransferrin PMID: 3658709
5. evidence suggests that conalbumin (ovotransferrin) and transferrin are products of the same gene, differing only in carbohydrate content PMID: 4907959
6. show both lobes are required for efficient iron binding and calculate binding kinetics. PMID: 6319414
7. ovotransferrin folds into two compact, iron-binding domains; the authors demonstrate that the duplicated domain structure is necessary to retain ovotransferrin in plasma and stop immediate loss via kidney filtration PMID: 6805466
8. The structure of ovotransferrin shows that the iron-binding site is located in the interdomain cleft in each lobe; differences in ovotransferrin structure cause changes to iron binding & uptake/release compared to lactotransferrin & transferrin. PMID: 7490743
9. At a pH where the protein net charge is negative (pH 8.0), the behavior of ovotransferrin at the air-water interface is more influenced by charge effects rather than bulk concentration effects. PMID: 21316692
10. Trp-Asn-Ile-Pro and Gly-Trp-Asn-Ile peptides of ovotransferrin showed the highest antioxidant activity. PMID: 20568771
11. Marked stabilization effects by amino(N)- and carboxyl(C)-terminal lobes of ovotransferrin are induced during iron binding, primarily upon N-lobe iron binding in the iron-free C-lobe and secondarily upon C-lobe iron binding in the monoferric N-lobe. PMID: 15323571
12. Ovotransferrin is able to cleave itself through the unique chemical reactivity of four tripeptides motifs, HTT (residues 209-211), HST (residues 542-544) and two CHT (residues 115-117 and 454-456). PMID: 16442235
13. Several proteins associated with the egg shell membranes (ESM) with antibacterial activity have been identified including ovotransferrin, in addition, pure fractions of ovotransferrin were obtained from egg white. PMID: 16721662
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亞細胞定位：

Secreted.
蛋白家族：

Transferrin family
組織特異性：

Expressed in the magnum of the oviduct (at protein level).
數據庫鏈接：

KEGG: gga:396241

UniGene: Gga.2551

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