Osm Antibody

^{Rare Species}

中文名稱：

Osm兔多克隆抗體
貨號：

CSB-PA723970LA01RA
規格：

￥440
圖片：
Immunofluorescent analysis of HepG2 cells using CSB-PA723970LA01RA at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情

標記方式：

Non-conjugated

本頁面中的產品，Osm Antibody (CSB-PA723970LA01RA)，的標記方式是Non-conjugated。對于Osm Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA723970LB01RA	Osm Antibody, HRP conjugated	ELISA
FITC	CSB-PA723970LC01RA	Osm Antibody, FITC conjugated
Biotin	CSB-PA723970LD01RA	Osm Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
基因功能參考文獻：
1. OSM is a key mediator for inducing differentiation of OC15-5 cells into hepatocytes PMID: 15743783
2. In the immortalized mouse and primary cultured proliferative rat hepatocytes, treatment with OSM markedly increased mRNA and protein of claudin-2 together with formation of developed networks of TJ strands. PMID: 17434483
3. OSM may not only play a role in the regulation of Sertoli cell proliferation and the initiation of spermatogenesis but may also play a role in the regulation of Leydig cell progenitor formation. PMID: 17996055
4. Results indicate that osteosarcoma cells stably producing OSM do not develop resistance to this cytokine and thus could be a valuable new tool to study the anti-cancer effect of OSM in vivo. PMID: 19168167
亞細胞定位：

Secreted.
蛋白家族：

LIF/OSM family
組織特異性：

Widely expressed. Expressed at higher levels in liver, skin and spleen.
數據庫鏈接：

KEGG: rno:289747

STRING: 10116.ENSRNOP00000032548

UniGene: Rn.127158

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