OXCT1 Antibody
-
中文名稱：OXCT1兔多克隆抗體
-
貨號：CSB-PA095719
-
規格：￥1100
-
圖片：
-
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: CSB-PA095719(OXCT1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
-
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：
-
別名：3 oxoacid CoA transferase 1 antibody; 3-oxoacid CoA-transferase 1 antibody; EC 2.8.3.5 antibody; OTTHUMP00000120012 antibody; OTTHUMP00000221550 antibody; OXCT antibody; Oxct1 antibody; SCOT antibody; Scot S antibody; Scot-S antibody; SCOT1_HUMAN antibody; Somatic type succinyl CoA:3 oxoacid CoA transferase antibody; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase antibody; Succinyl CoA:3 ketoacid CoA transferase antibody; Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial antibody; Succinyl CoA:3 oxoacid CoA transferase antibody; Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse,Rat
-
免疫原：Fusion protein of Human OXCT1
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
抗體亞型：IgG
-
純化方式：Antigen affinity purification
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
-
產品提供形式：Liquid
-
應用范圍：ELISA,WB
-
推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
-
基因功能參考文獻：
- Crystal structure of human SCOT, providing a molecular understanding of the reported mutations based on their potential structural effects. PMID: 23420214
- Case Report: Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency causes episodic ketoacidotic crises and no apparent symptoms between them. PMID: 20652411
- Data show that the ketone body metabolizing enzymes BDH1, BDH2, OXCT1 and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines. PMID: 21791085
- Missense Mutations in succinyl-CoA:3-ketoacid CoA transferase is associated with Ketoacidosis. PMID: 21296660
- Results demonstrate that h-Scot-t is a single intronless gene specifically expressed in the testis. PMID: 11756565
- In SCOT-deficient patients retaining some residual activity, permanent ketosis may be absent. PMID: 15496607
- A 6-bp deletion at the splice donor site of intron 1 resulted in the absence of a full-length mature SCOT mRNA with faint amounts of aberrantly spliced transcripts using a cryptic splice donor site within exon 1. PMID: 16765626
- the R268H mutation is a ketoacidosis-causing one PMID: 17706444
- liver-specific silencing of the SCOT gene expression may be mediated in part by its 5'-flanking sequence PMID: 18648183
- The activities of pyruvate carboxylase (SCOT) were decreased by 65% in pancreatic islets of patients with type 2 diabetes. PMID: 19296078
顯示更多
收起更多
-
相關疾?。?/div>Succinyl-CoA:3-oxoacid CoA transferase deficiency (SCOTD)亞細胞定位：Mitochondrion matrix.蛋白家族：3-oxoacid CoA-transferase family組織特異性：Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
