OVAL Antibody

^{Rare Species}

說(shuō)明書

中文名稱：

OVAL兔多克隆抗體
貨號(hào)：

CSB-PA271972
規(guī)格：

￥1100
圖片：
Gel: 10%SDS-PAGE, Lysate: 0.4 μg, 0.8 μg, Lane 1-2: 0.4 μg, 0.8 μg OVAL protein, Primary antibody: CSB-PA271972(OVAL Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情

產(chǎn)品詳情

Uniprot No.：

P01012
基因名：

SERPINB14
別名：

Allergen Gal d II antibody; Egg albumin antibody; OVAL_CHICK antibody; Ovalbumin antibody; Plakalbumin antibody; Serpin peptidase inhibitor antibody; SERPINB14 antibody
宿主：

Rabbit
反應(yīng)種屬：

Chicken
免疫原：

OVAL protein
免疫原種屬：

Gallus gallus (Chicken)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Non-inhibitory serpin. Storage protein of egg white.
基因功能參考文獻(xiàn)：
1. 120A and C30/73/120A mutants formed no SS form, in contrast to C73/120A as a control. Thus, we concluded that Cys30 participates in the correct folding of OVA, and that its SS bond (Cys11-Cys30) is transiently generated during the early folding stage to avoid misfolding, and then the native SS form of OVA is regenerated through SH-SS exchanges. PMID: 29175210
2. Data show that both ovalbumin and ovomucoid were efficiently mutagenized in cultured primordial germ cells (PGCs) by CRISPR/Cas9 system. PMID: 27050479
3. Data show that both green and red light wavelengths induce structural changes in ovalbumin. PMID: 26656181
4. found that ovalbumin packs into a bicontinuous structure with a significant void space and that ovalbumin is highly ordered within the dense network PMID: 26488663
5. Cluster analysis revealed a first group of proteins related to mineralization and mainly present at the onset of calcification including OVOT, OVAL, OC-17, and two novel calcium binding proteins (EDIL3, MFGE8). PMID: 25284052
6. Secondary and tertiary structures of OVA were characterised to show the relationship between potential allergenicity and the conformation of OVA after heating and glycation. PMID: 23915026
7. Inhalation tolerance limits aeroallergen OVA peptide capture by airway mucosal dendritic cell subsets via a mechanism of bone marrow suppression of dendritic cell precursor function coupled with reduced antigen availability in vivo at the airway mucosa. PMID: 21930961
8. Lysozyme (pI = 9.3) destabilizes the liquid amorphous calcium carbonate emulsion whereas the glycoprotein ovalbumin (pI = 4.7) extends the lifespan of the emulsified state remarkably. PMID: 21736300
9. Fibrosarcoma-secreting vesicle-bound ovalbumin elicits a strong antigen-specific CD8-type T cell response, CD4-positive T cell help, antigen-specific antibodies, and a decrease in the percentage of immunosuppressive regulatory T cells in the tumor. PMID: 21705625
10. The presence of the original SS bridge in ovalbumin contributes to conformational stability but is not directly related to the conversion to heat-stable ovalbumin (S-OVA). PMID: 21389617
11. These authors report the kinetics for the rate of acetylation during protein synthesis using ovalabumin. PMID: 272676
12. Reports details of the organization of the ovalbumin gene exon-intron structure. PMID: 283395
13. Authors measure the kinetics of mRNA binding to microsomes during translation & nascent chain elongation rates. PMID: 6749856
14. Demonstrates the kinetics of I-ovalbumin conformer serine peptidase inhibition. PMID: 8939987
15. Demonstrates that the I-ovalabumin conformer binds bovine trypsin PMID: 15488772
16. Results provide a detailed equilibrium and kinetic characterization of the interaction between the serpin ovalbumin and bovine trypsin. PMID: 15488772
17. the carbohydrate chain and two phosphate moieties do not affect hydrophobic collapse in the kinetic refolding of hen ovalbumin but play an important role in the slow rearrangement, by blocking the off-pathway reaction that competes with correct refolding PMID: 15618616
18. Chromatin immunoprecipitation assays showed that the ovalbumin control region was associated with acetylated histone H3 but not with dimethylated histone H3 at Lys 27. PMID: 16794325
19. Intracerebral, but not systemic, infection with attenuated Listeria-secreting ovalbumin induces a neurological model syndrome in transgenic neuron-specific enolase-OVA mice after brain bacterial clearance, whereas wild-type mice remain healthy. PMID: 18523310
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亞細(xì)胞定位：

Secreted.
蛋白家族：

Serpin family, Ov-serpin subfamily
組織特異性：

Major protein of egg white. Expressed in the magnum of the oviduct (at protein level).
數(shù)據(jù)庫(kù)鏈接：

KEGG: gga:396058

STRING: 9031.ENSGALP00000036403

UniGene: Gga.623

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