ONECUT2 Antibody, FITC conjugated
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中文名稱：ONECUT2兔多克隆抗體, FITC偶聯
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貨號：CSB-PA016337LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ONECUT2 Polyclonal antibody
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Uniprot No.：
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基因名：ONECUT2
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別名：ONECUT2 antibody; HNF6B antibody; One cut domain family member 2 antibody; Hepatocyte nuclear factor 6-beta antibody; HNF-6-beta antibody; One cut homeobox 2 antibody; Transcription factor ONECUT-2 antibody; OC-2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human One cut domain family member 2 protein (214-331AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.
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基因功能參考文獻：
- Bioinformatics-based prediction, combined with qRT-PCR analysis and Western blotting, identified Onecut2 and SIRT1 as the 2 prominent miR-9 target genes under the conditions tested. In this study, Onecut2 and SIRT1 were confirmed as miR-9 target genes, which will help future investigations to probe in greater detail the role of miR-9 in Nonalcoholic Fatty Liver Disease. PMID: 27756894
- Data show that ONECUT2, IGF2BP1, and ANXA2 proteins were confirmed to be microRNA-9 (miR-9) targets and aberrantly upregulated in hepatocellular carcinoma (HCC). PMID: 26547929
- our data showed that transcript factor Onecut2 is involved in the EMT, migration and invasion of CRC cells; miR-429 inhibits the initiation of EMT and regulated expression of EMT-related markers PMID: 24402783
- Mutations at the -5/-6 site of the F9 promotor account for the majority of hemophilia B Leyden cases and disrupt the binding of ONECUT1 and ONECUT2. PMID: 23472758
- OC2 transcription factor is a direct target of T-bet in type-1 T-helper cells. PMID: 18418398
- A CpG island proximal to ONECUT2 is frequently methylated in diffuse large B-cell lymphoma (DLBCL). PMID: 18288132
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亞細胞定位：Nucleus.
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蛋白家族：CUT homeobox family
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數據庫鏈接：
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