NUP50 Antibody

說明書

產品詳情

Uniprot No.：

Q9UKX7
基因名：

NUP50
別名：

50 kDa nucleoporin antibody; NPAP60 antibody; NPAP60L antibody; Nuclear pore associated protein 60L antibody; Nuclear pore complex protein Nup50 antibody; Nuclear pore-associated protein 60 kDa-like antibody; Nucleoporin 50 antibody; Nucleoporin 50kDa antibody; Nucleoporin Nup50 antibody; Nup50 antibody; NUP50_HUMAN antibody; PRO1146 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human NUP50
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
基因功能參考文獻：
1. Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha5. PMID: 22130666
2. Results suggest that Npap60L and Npap60S function differently in nuclear protein import. PMID: 20016008
亞細胞定位：

Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
組織特異性：

Ubiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
數據庫鏈接：

HGNC: 8065

OMIM: 604646

KEGG: hsa:10762

STRING: 9606.ENSP00000345895

UniGene: Hs.475103

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