NRG2 Antibody
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中文名稱：NRG2兔多克隆抗體
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貨號：CSB-PA005145
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規格：￥1090
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圖片：
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Western Blot analysis of HT29 cells using Neuregulin-2 Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：Divergent of neuregulin 1 antibody; Divergent of neuregulin-1 antibody; Don 1 antibody; DON-1 antibody; Neural- and thymus-derived activator for ERBB kinases antibody; Neuregulin 2 antibody; Neuregulin-2 antibody; NRG-2 antibody; Nrg2 antibody; NRG2_HUMAN antibody; NTAK antibody; Pro NRG2 antibody; Pro-NRG2 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Synthesized peptide derived from the Internal region of Human Neuregulin-2.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:20000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
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基因功能參考文獻：
- reduced expression of NRG2 led to marginal increase in cell survival under arsenite-induced stress. PMID: 27345716
- examination of the effect of isoforms on angiogenesis PMID: 14722120
- Nrg-2-induced Acetylcholine Receptor transcription requires an N-box motif and is regulated by alternative splicing. PMID: 15961242
- Linkage interval for GLC1M was refined to a smaller region. The NRG2 gene was excluded as the causative gene for juvenile-onset primary open angle glaucoma. PMID: 17563728
- Gln43 of NRG2beta is both necessary and sufficient for NRG2 stimulation of ErbB4 coupling to IL3 independence. PMID: 17945187
- NRG2 was positive in almost all breast cancers studied. High expression is related to the biological aggressiveness of breast cancer. PMID: 17962208
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亞細胞定位：[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-2]: Secreted.
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蛋白家族：Neuregulin family
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組織特異性：Restricted to the cerebellum in the adult.
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數據庫鏈接：
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