NR6A1 Antibody
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中文名稱：NR6A1兔多克隆抗體
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貨號：CSB-PA016067GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：GCNF 1 antibody; GCNF antibody; GCNF1 antibody; Germ cell nuclear factor antibody; hGCNF antibody; hRTR antibody; NR 61 antibody; NR61 antibody; nr6a1 antibody; NR6A1_HUMAN antibody; Nuclear receptor subfamily 6 group A member 1 antibody; Orphan nuclear receptor NR6A1 antibody; Retinoic acid receptor related testis associated receptor antibody; Retinoid receptor related testis specific receptor antibody; Retinoid receptor-related testis-specific receptor antibody; RTR antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human NR6A1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis.
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基因功能參考文獻：
- GCNF acts as a transcriptional repressor in the regulation of OCT4 gene expression through cooperative interaction with three NR binding elements in pluripotent NCCIT cells. PMID: 29057499
- the genes, and up-regulated 64% in undifferentiated hES cells. In addition, GCNF also showed a regulatory gene pattern that is different from RA treatment during hES cell differentiation PMID: 26769970
- Findings show a role for Gcnf as a regulator of iPS cell pluripotency gene expression. It also demonstrates that reactivation of the Gcnf gene may serve as a marker to distinguish completely reprogrammed iPS cells from incompletely pluripotent cells. PMID: 23495137
- Our results show that cellular levels of NR6A1 are correlated with disease progression in prostate cancer. PMID: 23532770
- These experiments confirmed that NR6A1 works as a regulator for hypocretin transcription. PMID: 21056546
- RTR mRNA was expressed in the human placental choriocarcinoma cell lines BeWo, JAR, and JEG-3. PMID: 11969338
- characterization of a novel nuclear protein, referred to as RAP80, that interacts with the retinoid-related testis-associated receptor PMID: 12080054
- down-regulation of CREMtau-mediated gene expression by GCNF PMID: 15456763
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亞細胞定位：Nucleus.
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蛋白家族：Nuclear hormone receptor family, NR6 subfamily
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組織特異性：Shows highest expression in the germ cells of the adult testis.
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數據庫鏈接：
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