NPFF Antibody

說明書

中文名稱：

NPFF兔多克隆抗體
貨號：

CSB-PA015981ESR2HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA015981ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA015981ESR2HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NPFF Polyclonal antibody
Uniprot No.：

O15130
基因名：

NPFF
別名：

NPFF antibody; Pro-FMRFamide-related neuropeptide FF antibody; FMRFamide-related peptides) [Cleaved into: Neuropeptide SF antibody; NPSF); Neuropeptide FF antibody; NPFF); Neuropeptide AF antibody; NPAF)] antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Pro-FMRFamide-related neuropeptide FF protein (34-113AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
基因功能參考文獻：
1. Our results...highlight the neuropeptide FF-amide peptide encoding gene (NPFF) as a novel candidate risk gene for both migraine with aura and migraine without aura PMID: 26660531
2. reduction of NPFF release within the dorsal motor nucleus and ambiguus nucleus could serve as a possible cause of the impairment of cardiac vagal control in hypertensive patients PMID: 21120930
3. expression of hNPFF2 receptor mRNA was up-regulated by neuropeptide FF PMID: 16336216
4. neuropeptide FF and micro-opioid receptor association could be a possible molecular basis for anti-opioid activity PMID: 17224450
5. the findings from the early studies on the analgesic and morphine modulating activities suggested a role for NPFF in pain modulation--review PMID: 17854890
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亞細胞定位：

Secreted.
蛋白家族：

FARP (FMRFamide related peptide) family
數據庫鏈接：

HGNC: 7901

OMIM: 604643

KEGG: hsa:8620

STRING: 9606.ENSP00000267017

UniGene: Hs.733076

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