NKX2-6 Antibody
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中文名稱：NKX2-6兔多克隆抗體
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貨號：CSB-PA877108
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規格：￥2024
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圖片：
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Western blot analysis of extracts from HeLa cells and COLO cells, using NKX26 antibody.
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) NKX2-6 Polyclonal antibody
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Uniprot No.：
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基因名：NKX2-6
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from internal of Human NKX26.
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免疫原種屬：Homo sapiens (Human)
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克隆類型：Polyclonal
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:3000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Acts as a transcriptional activator. In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development.
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基因功能參考文獻：
- This study firstly links NKX2.6 loss-of-function mutation with increased susceptibility to isolated VSD. PMID: 25380965
- Data associated genetically defective NK2 homeobox 6 (NKX2-6) with enhanced susceptibility to atrial fibrillation (AF). PMID: 25319568
- Heterozygous mutations in Nkx2.6, p.V176M and p.K177X, were identified in 2 unrelated patients, one with tetralogy of Fallot and one with double outlet of right ventricle and ventricular septal defect. Increased vulnerability to TOF or DORV is discussed. PMID: 25195019
- NKX2-6 plays a role in human cardiogenesis. PMID: 24421281
- weakly activates transcription of a Cx40 promoter, may have role in heart development PMID: 15649947
- NKX2.5/NKX2.6 mutations are not a common cause of isolated type 1 truncus arteriosus in a small cohort of multiethnic cases. PMID: 18939937
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相關疾病：Conotruncal heart malformations (CTHM)
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亞細胞定位：Nucleus.
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蛋白家族：NK-2 homeobox family
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數據庫鏈接：
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